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EPA/OCSPP RIN: 2070-AD16 Publication ID: Fall 2010 
Title: High Production Volume (HPV) Chemicals; Testing of Certain Chemicals 
Abstract: EPA has or is developing several test rules under section 4(a) of the Toxic Substances Control Act (TSCA) to require testing and recordkeeping requirements for certain high production volume (HPV) chemicals (i.e., chemicals which are manufactured (including imported) in the aggregate at more than 1 million pounds on an annual basis) that have not been sponsored under the voluntary HPV Challenge Program. Although varied based on specific data needs for the particular chemical, the data generally collected under these rules may include: acute toxicity, repeat dose toxicity, developmental and reproductive toxicity, mutagenicity, ecotoxicity, and environmental fate. The first rule proposed testing for 37 HPV chemicals with substantial worker exposure. When finalized in 2006, the number of chemicals included in the first final rule was reduced to 17 based on new information on annual production volumes, worker exposure, and commitments to the voluntary HPV Challenge Program. A second proposed test rule that published in 2008 for 19 chemicals is expected to be finalized in 2010. A third proposed test rule that published in early 2010 for 29 chemicals is expected to be finalized in 2011. 
Agency: Environmental Protection Agency(EPA)  Priority: Substantive, Nonsignificant 
RIN Status: Previously published in the Unified Agenda Agenda Stage of Rulemaking: Final Rule Stage 
Major: No  Unfunded Mandates: No 
CFR Citation: 40 CFR 790 to 799   
Legal Authority: 15 USC 2603   
Legal Deadline:  None
Timetable:
Action Date FR Cite
NPRM  12/26/2000  65 FR 81658   
Final Action  03/16/2006  71 FR 13709   
Direct Final Action1; Revocation; Coke-Oven Light Oil (Coal)  12/08/2006  71 FR 71058   
NPRM2  07/24/2008  73 FR 43314   
NPRM3  02/25/2010  75 FR 8575   
Direct Final Action1-2; Revocation  12/00/2010    
Final Action2  12/00/2010    
NPRM4  04/00/2011    
Final Action3  04/00/2011    
Additional Information: EPA Docket information: EPA-HQ-OPPT-2005-0033; EPA-HQ-OPPT-2007-0531; EPA-HQ-OPPT-2009-0112
Regulatory Flexibility Analysis Required: No  Government Levels Affected: Federal 
Small Entities Affected: Businesses  Federalism: No 
Included in the Regulatory Plan: No 
International Impacts: This regulatory action will be likely to have international trade and investment effects, or otherwise be of international interest.
RIN Information URL: http://www.epa.gov/opptintr/chemtest  
Sectors Affected: 32411 Petroleum Refineries; 325 Chemical Manufacturing 
RIN Data Printed in the FR: No 
Agency Contact:
Paul Campanella
Environmental Protection Agency
Office of Chemical Safety and Pollution Prevention
7405M,
Washington, DC 20460
Phone:202 564-8091
Email: Campanella.Paul@epa.gov

John Schaeffer
Environmental Protection Agency
Office of Chemical Safety and Pollution Prevention
7405M,
Washington, DC 20460
Phone:202 564-8173
Fax:202 564-4765
Email: schaeffer.john@epa.gov