FSIS is proposing to revise the regulations prescribing the statistical methods to be used in measuring the performance of chemistry laboratories in its voluntary Accredited Laboratory Program (ALP) and to expand the program to include pathogen testing. FSIS also is proposing that initial screening for pathogens on official samples may be conducted by laboratories accredited under this program. Additionally, the Agency is proposing to make various minor edits and changes to the regulation for the sake of clarity, to incorporate all sample types under the jurisdiction of FSIS as appropriate for the associated analyses, and to improve program flexibility.