The Bureau of Industry and Security (BIS) is amending the Export Administration Regulations (EAR) to reflect decisions made at the November 2021 and March 2022 Australia Group (AG) Virtual Implementation Meetings and the AG Plenary Meeting held in July 2022.  Consistent with decisions made at the AG Virtual Implementation Meetings, this rule amends Export Control Classification Number (ECCN) 1C353 on the Commerce Control List to clarify that the controls on genetic elements and genetically modified organisms include, inter alia, any gene(s) or translated product(s) specific to any controlled virus.  In addition, ECCN 2B352 is amended to clarify the scope of the exclusion that applies to medical isolators "specially designed” for barrier nursing or transportation of infected patients.  Consistent with the decisions made at the July 2022 Plenary Meeting, this final rule amends ECCN 1C351 by adding four naturally occurring, dual-use marine toxins (specifically, brevetoxins, gonyautoxins, nodularins and palytoxin) and removing cholera toxin.  The addition of these four toxins is consistent with the emerging and foundational technologies requirement in Section 1758 of the Export Control Reform Act of 2018 (ECRA) (50 U.S.C. 4801-4852), as codified under 50 U.S.C. 4817.  This rule also amends ECCN 1C354 to reflect the AG Plenary updates to the nomenclature of certain bacteria and fungi.  In addition, ECCN 2B352 is amended to reflect an AG clarification to the definition of disinfected” as it applies to certain biological equipment.