EPA is developing a final significant new use rule (SNUR) under section 5(a)(2) of the Toxic Substances Control Act (TSCA) for certain ethylene glycol ethers (also known as glymes). EPA issued a proposed rule on July 12, 2011. This rule will require persons who intend to manufacture (including import) or process certain ethylene glycol ethers for an activity that is designated as a significant new use by this rule to notify EPA at least 90 days before commencing any significant new use. The required notifications will provide EPA with the opportunity to evaluate the intended use and, if necessary, to prohibit or limit that activity before it occurs.