EPA is considering proposing to update the exemptions from regulation under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) and the Federal Food, Drug, and Cosmetic Act (FFDCA) for certain plant incorporated protectant (PIP) products to reflect newer technologies, i.e., the exemptions are from the requirements to obtain a pesticide registration under FIFRA and establish a tolerance or tolerance exemption for residues in or on food commodities under FFDCA. EPA regulations (40 CFR 174.3) define a PIP as a pesticidal substance that is intended to be produced and used in a living plant, or in the produce thereof, and the genetic material necessary for production of such a pesticidal substance. It also includes any inert ingredient contained in the plant, or produce thereof.” EPA currently regulates all PIPs except those exempted by regulation at 40 CFR 174.25 and 174.508. This action is intended to fulfill section 4(b) of Executive Order 13874 (84 FR 27899, June 11, 2019) on Modernizing the Regulatory Framework for Agricultural Biotechnology Products.