In this rulemaking, PHMSA would amend the Hazardous Materials Regulations (HMR) to modernize and streamline the HMR, where necessary, to facilitate the transportation of hazardous materials involved in U.S. space operations. PHMSA will aim to identify problems and friction with the current regulatory scheme, and potentially reduce burdens on both PHMSA and the regulated community while advancing U.S. interests in the space industry. PHMSA would coordinate closely with its interagency partners (Department of Defense, National Aeronautics and Space Administration, etc.) and its modal partners (Federal Aviation Administration, Federal Motor Carrier Safety Administration, Federal Railroad Administration, and U.S. Coast Guard) to ensure a comprehensive approach that allows for the seamless movement of goods across multiple modes of transport while allowing for the specific needs of each mode to be safely addressed.