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EPA is developing a significant new use rule (SNUR) under section 5(a)(2) of the Toxic Substances Control Act (TSCA) for certain chemical substances commonly known as nonylphenols (NP) and nonylphenol ethoxylates (NPE). On October 1, 2014, EPA proposed to designate any use of 13 NPs and NPEs as a "significant new use." EPA also proposed that, for 2 additional NPs, any use other than as an intermediate or as an epoxy cure catalyst would constitute a "significant new use." The SNUR would require persons who intend to manufacture (including import) or process these chemical substances to notify EPA at least 90 days before commencing that activity. The required notification would provide EPA with the opportunity to evaluate the intended use and, if necessary, to prohibit or limit that activity before it occurs, to prevent unreasonable risk to human health or the environment.