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OMB Control No: 0920-0728	ICR Reference No: 202609-0920-007
Status: Received in OIRA	Previous ICR Reference No: 202504-0920-009
Agency/Subagency: HHS/CDC	Agency Tracking No: 0920-0728
Title: [OPHDST] National Notifiable Diseases Surveillance System (NNDSS)
Type of Information Collection: Revision of a currently approved collection	Common Form ICR: No
Type of Review Request: Regular	Date Submitted to OIRA: 10/19/2026

	Requested	Previously Approved
Expiration Date	36 Months From Approved	11/30/2028
Responses	12,576	7,276
Time Burden (Hours)	33,471	18,354
Cost Burden (Dollars)	0	0

Abstract: The National Notifiable Diseases Surveillance System (NNDSS) is the nation’s public health surveillance system used to monitor the occurrence and spread of nationally notifiable conditions. Respondents are 60 jurisdictions: public health departments in every U.S. state, New York City, Washington DC, 5 U.S. territories (American Samoa, the Commonwealth of Northern Mariana Islands, Guam, Puerto Rico, and the U.S. Virgin Islands), and 3 freely associated states (the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau). NNDSS provides the official source of statistics in the United States for nationally notifiable conditions and CDC is the sole repository for these national, population-based data. Recently the NNDSS platform was modernized and expanded as a low-cost, common portal for collecting information on other conditions. Among the thousands of diseases that affect the health of the population, CDC and the Council of State and Territorial Epidemiologists (CSTE) have prioritized the approximately 120 Nationally Notifiable Conditions as those most important for public health monitoring and response. Changes to NNDSS in this Revision include: 1) receipt of case notification data for soil-transmitted helminth infections and flea-borne typhus since they are under standardized surveillance; 2) receipt of two new disease-specific data elements for leprosy (Hansen’s disease); 3) 45 new core data elements for all conditions; and 4) the addition of up to 50 Tribal Nations to the respondent population. The estimated annual burden hours increased due to the inclusion of up to 50 Tribal Nations.

Authorizing Statute(s): US Code: 42 USC 241 Name of Law: PHSA

Citations for New Statutory Requirements: None

Associated Rulemaking Information
RIN:	Stage of Rulemaking:	Federal Register Citation:	Date:
	Not associated with rulemaking

Federal Register Notices & Comments
60-day Notice:	Federal Register Citation:	Citation Date:
	91 FR 17654	04/07/2026
30-day Notice:	Federal Register Citation:	Citation Date:
	91 FR 63287	10/05/2026
Did the Agency receive public comments on this ICR? Yes

ICR Summary of Burden

	Total Request	Previously Approved	Change Due to Agency Discretion
Annual Number of Responses	12,576	7,276	5,300
Annual Time Burden (Hours)	33,471	18,354	15,117
Annual Cost Burden (Dollars)	0	0	0

Burden increases because of Program Change due to Agency Discretion: Yes

Burden Increase Due to: Miscellaneous Actions

Burden decreases because of Program Change due to Agency Discretion: No

Burden Reduction Due to:

Short Statement: Revision of 0920-0728 results in an increase to 33,471 estimated annual burden hours due to the inclusion of up to 50 Tribal Nations.

Annual Cost to Federal Government: $98,573,020

Does this IC contain surveys, censuses, or employ statistical methods? No

Does this ICR request any personally identifiable information (see OMB Circular No. A-130 for an explanation of this term)? Please consult with your agency's privacy program when making this determination. Yes

Does this ICR include a form that requires a Privacy Act Statement (see 5 U.S.C. §552a(e)(3))? Please consult with your agency's privacy program when making this determination. Yes

Is this ICR related to the Affordable Care Act [Pub. L. 111-148 & 111-152]? No

Is this ICR related to the Dodd-Frank Wall Street Reform and Consumer Protection Act, [Pub. L. 111-203]? No

Is this ICR related to the American Recovery and Reinvestment Act of 2009 (ARRA)? No

Is this ICR related to the Pandemic Response? Yes

Agency Contact: Jeffrey Zirger 404 639-7118 wtj5@cdc.gov

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