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EPA is considering a TSCA section 6(a) rule to address the unreasonable risk presented by laboratory use of chemicals that have undergone a TSCA risk evaluation. Laboratories perform important functions such conducting environmental monitoring needed for cleanup sites and wastewater treatment. Section 6 of TSCA requires EPA to regulate to the extent necessary a chemical substance that the Administrator has determined presents unreasonable risk under the conditions of use, which will almost always include use as a laboratory chemical. EPA is initiating a rulemaking so that the requirements for laboratories are consistent for all chemicals evaluated under TSCA section 6. EPA intends to consider the existing Occupational Safety and Health Administration (OSHA) standards, including OSHA's laboratory standard, during the development of this rule to avoid conflicting or duplicative regulation. EPA will solicit public comment through a notice of proposed rulemaking.