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The direct final rule amends the Commission's regulations in 10 CFR part 73 to remove the Safeguards Information Modified Handling (SGI-M) designation of the security related information for large irradiators, manufacturer and distributors, and for transport of category 1 quantities of radioactive material. The rulemaking will also result in the removal of the SGI-M designation of the security-related information for the transportation of irradiated reactor fuel that weighs 100 grams or less in net weight of irradiated fuel. The security-related information for these facilities and the transportation of certain materials will no longer be designated as SGI-M and will be protected under the information protection requirements that apply to other materials licensees that possess category 1 and category 2 quantities of radioactive material. This approach achieves sufficient protection of sensitive information while facilitating effective implementation of the part 37 requirements. Conforming changes would be made to 10 CFR parts 30, 37, and 150.