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HHS/CDC RIN: 0920-AA79 Publication ID: Fall 2022 
Title: Possession, Use, and Transfer of Select Agents and Toxins; Addition of SARS-CoV/SARS-CoV-2 Chimeric Viruses 

With this rulemaking, HHS/CDC will add SARS-CoV/SARS-CoV-2 chimeric viruses to the HHS list of select agents and toxins.

Agency: Department of Health and Human Services(HHS)  Priority: Other Significant 
RIN Status: Previously published in the Unified Agenda Agenda Stage of Rulemaking: Final Rule Stage 
Major: No  Unfunded Mandates: No 
CFR Citation: 42 CFR 73   
Legal Authority: secs. 201 to 204 and 221 of title II of Pub. L. 107-188 (42 U.S.C. 262a)   
Legal Deadline:  None
Action Date FR Cite
Interim Final Rule  11/17/2021  86 FR 64075   
Interim Final Rule Effective  11/17/2021 
Interim Final Rule Comment Period End  01/18/2022 
Final Action  04/00/2023 
Regulatory Flexibility Analysis Required: No  Government Levels Affected: State 
Small Entities Affected: No  Federalism: No 
Included in the Regulatory Plan: No 
International Impacts: This regulatory action will be likely to have international trade and investment effects, or otherwise be of international interest.
RIN Data Printed in the FR: No 
Agency Contact:
Samuel Edwin Ph. D.
Director, Division of Select Agents and Toxins
Department of Health and Human Services
Centers for Disease Control and Prevention
1600 Clifton Road NE, H21-7,
Atlanta, GA 30329
Phone:404 718-2000