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The Toxic Substances Control Act (TSCA) directs EPA to take expedited action on certain persistent, bioaccumulative, and toxic (PBT) chemicals to address the risks of injury to health or the environment presented by the chemical substance and reduce exposure to the substance to the extent practicable. Consistent with that mandate, final risk management rules restricting the use of decabromodiphenyl ether (DecaBDE); phenol, isopropylated phosphate (3:1) (PIP (3:1)), 2,4,6-tris(tert-butyl)phenol (2,4,6-TTBP); hexachlorobutadiene (HCBD); and pentachlorothiophenol (PCTP) were issued in January 2021 and went into effect in February 2021. EPA is developing a proposed rule to amend TSCA section 6(h) regulations for PIP (3:1) and DecaBDE to further reduce exposures, promote environmental justice, and better protect human health and the environment. EPA is continuing to consider whether to propose amendments to TSCA section 6(h) regulations for 2,4,6-TTBP, HCBD, and PCTP in one or more separate actions.